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Associate Professor

University of Central Oklahoma
gxu@uco.edu (405) 974-5423 Engineering & Physics STEM 241 , Box 87

Education and Certifications

Washington University (St. Louis, MO): M.S. and D.Sc. in Biomedical Engineering, 2001-2006

Fudan University (Shanghai, China): B.S. in Theoretical & Applied Mechanics, 1994-1998
                                                           M.S. in Fluid Mechanics (Biomechanics), 1998-2001

 

Experience

University of Central Oklahoma, Edmond, OK
2017-           Associate Professor, Engineering and Physics

2012-2017   Assistant Professor, Engineering and Physics

Washington University, St. Louis, MO

2011-2012   Research Associate, Mechanical Engineering and Materials Science
2009-2011   Research Assistant Professor, Biomedical Engineering
2006-2009   Postdoctoral Research Associate, Biomedical Engineering

Honors and Awards

Faculty Merit Credit Award for Research - 2017

CMS Outstanding Spirit Award - 2016
Faculty Merit Credit Award for Research - 2015
Herbert S. Dordick Award for an Outstanding Mentor - 2014

 

Classes Taught

Introduction to Biomedical Engineering                                

Principles of Biomedical Engineering

Biomedical Engineering Lab

Biomechanics

Statics

Strength of Materials

Fluid Mechanics

Fluid Mechanics Lab

Heat Transfer Lab

Vibrations

Interests

Cell and tissue biomechanics

Developmental biomechanics

Optical coherence tomography

Micropipette aspiration and manipulation

Research, Published Work, and Scholarly Activities

  1. M.B. Vaughan, G. Xu, T.L. Morris, P. Kshetri, J.X. Herwig. 2019. Predictable fibroblast tension generation by measuring compaction of anchored collagen matrices using microscopy and optical coherence tomography. Cell Adhesion & Migration, 13:1, 303-314.

  2. K.T. Doan, P. Kshetri, N. Attamakulsri, D.R. Newsome, F. Zhou, C.K. Murray, W.R. Chen, G. Xu, M.B. Vaughan. 2019. The effect of chitosan derivatives on the compaction and tension generation of the fibroblast-populated collagen matrix. Molecules, 24(15), 2713.

  3. C.C. Obioma, E. Layton, K.T. Doan, G. Xu, F. Zhou, W.R. Chen, M.B. Vaughan. Effect of near infrared lasers and glycated chitosan on myofibroblast differentiation and contraction.  Proc. SPIE 10495, Biophotonics and Immune Responses XIII, 1049518, 2018. 

  4. G. Xu, K.S. Wilson, R.J. Okamoto, J.-Y. Shao, S.K. Dutcher, and P.V. Bayly. Flexural Rigidity and Shear Stiffness of Flagella Estimated from Induced Bends and Counterbends. Biophysical Journal, 110: 2759-2768, 2016. PMID: 27332134.  
  5. B.A. Filas*, G. Xu*, L.A.Taber. Probing regional mechanical properties of embryonic tissue using microindentation and optical coherence tomography. Methods in Molecular Biology – Tissue Morphogenesis, 1189: 3-16, 2015. (*Co-First Authorship) PMID: 25245683.
  6. V.D. Varner, G. Xu, L.A. Taber. Shape is not enough to test hypotheses for morphogenesis. In "Residual Stress, Thermomechanics & Infrared Imaging, Hybrid Techniques and Inverse Problems, Volume 8", Eds. M. Rossi et al. pp 325-331. Springer. 2014.
  7. Y. Shi, J. Yao, G. Xu, L.A. Taber. Bending of the looping heart: differential growth revisited. Journal of Biomechanical Engineering. 136: 081002-1-15, 2014. PMID: 24509638.
  8. P.V. Bayly, R.J. Okamoto, G. Xu, Y. Shi, L.A. Taber. A cortical folding model incorporating stress-dependent growth explains gyral wavelengths and stress patterns in the developing brain. Physical Biology, 10: 016005-1-12, 2013. PMID: 23357794.
  9. B.A. Filas, G. Xu, L.A. Taber. Mechanisms of brain morphogenesis. In “Computer Models in Biomechanics: from Nano to Macro”, Eds. G.A. Holzapfel, E. Kuhl. pp 337-349. Springer. 2013.
  10. G. Xu, A.K. Knutsen, K. Dikranian, C.D. Kroenke, P.V. Bayly, L.A. Taber. Axons pull on the brain, but tension does not drive cortical folding. Journal of Biomechanical Engineering,132: 071013-1-17. 2010. PMID: 20590291.
  11. G. Xu, P.S. Kemp, J.A. Hwu, A.M. Beagley, P.V. Bayly, L.A. Taber. Opening angles and material properties of the early embryonic chick brain. Journal of Biomechanical Engineering, 132: 011005-1-7. 2010. PMID: 20524743.
  12. G. Xu, P.V. Bayly, L.A. Taber. Residual stress in the adult mouse brain. Biomechanics & Modeling in Mechanobiology, 8: 253-262. 2009. PMID: 18651186.
  13. Y. Chen, B. Liu, G. Xu, J.-Y. Shao. Validation, in-depth analysis, and modification of the micropipette aspiration technique. Cellular & Molecular Bioengineering, 2: 351-365. 2009. PMID: 20333318.
  14. G. Xu and J.-Y. Shao.  Human neutrophil surface protrusion under a point load: location independence and viscoelasticity. American Journal of Physiology - Cell Physiology, 295: C1434-1444. 2008. PMID: 18815230.
  15. J.-Y. Shao and G. Xu. The adhesion between a microvillus-bearing cell and a ligand-coated substrate: a Monte Carlo study. Annals of Biomedical Engineering, 35: 397-407. 2007. PMID: 17151923.
  16. G. Xu and J.-Y. Shao. Double tether extraction from human neutrophils and its comparison with CD4+ T lymphocytes. Biophysical Journal, 88: 661-669. 2005. PMID: 15475589.
  17. J.-Y. Shao, G. Xu, and P. Guo. Quantifying cell-adhesion strength with micropipette manipulation: principle and application. Frontiers in Bioscience, 9: 2183-2191. 2004. PMID: 15353280.
  18. D.A. Voronov, P.W. Alford, G. Xu, L.A. Taber. The role of mechanical forces in dextral rotation during cardiac looping in the chick embryo. Developmental Biology, 272: 339-350. 2004. PMID: 15282152.

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